منابع مشابه
The Inheritance of Retinoblastoma and Its Relationship to Practical Eugenics*
In a brief review (5I), published several years ago, the author called attention to the fact that it was no longer possible to discuss the inheritance of predisposition to the development of neoplasms if all neoplasms were considered in one group. Satisfactory evidence was available even then that the significance of intrinsic factors, the part played by genes and by extrachromosomal factors, a...
متن کاملA review of retinoblastoma disease
Retinoblastoma is a rare type of eye cancer that usually occurs in early childhood, usually before the age of five. This type of cancer occurs in the retina, the light-sensitive tissue behind the eye that recognizes light and color. It is the most common type of eye cancer in children. One-third of all retinoblastomas are inherited, meaning that mutations in the RB1 gene are present in all cell...
متن کاملRetinoblastoma in Southwest Iran
Background: Retinoblastoma is the most common embryonic tumor of retina of children. This tumor include 3-4% of all children malignancies during the age range 0-14 years. In this study, we reported the incidence, therapeutic protocols, and treatment outcome of children with RB in South west Iran. Methods: We retrospectively investigated the medical reports clinical and pathological features of...
متن کاملMolecular Investigation of the Human Adenovirus in Retinoblastoma Patients
Background and Aims: Retinoblastoma tumors are the most common intraocular malignancy in childhood, leading to death after two years. The Human Adenovirus (HAdV) infection could be critical in the retinoblastoma pathogenesis due to the virus and retinoblastoma 1 interactions. The objective of the current study was to investigate the possible presence of the HAdV genome in the retinoblastoma pat...
متن کاملRetinoblastoma.
Retinoblastoma, a neuroblastic tumor, is the most common primary intraocular malignancy of childhood. Patients usually present with leukokoria (white reflex or white pupil), detected in primary care. The mean age at diagnosis is 12 months for bilateral tumors and 24 months for unilateral tumors. If untreated, almost all patients die of intracranial extension and disseminated disease within two ...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1969
ISSN: 0007-1161
DOI: 10.1136/bjo.53.3.212